diff --git a/model/labels/regexp.go b/model/labels/regexp.go
index a4bdf885ee..5f4f753419 100644
--- a/model/labels/regexp.go
+++ b/model/labels/regexp.go
@@ -71,6 +71,10 @@ func NewFastRegexMatcher(v string) (*FastRegexMatcher, error) {
 		if err != nil {
 			return nil, err
 		}
+
+		// Remove any capture operations before trying to optimize the remaining operations.
+		clearCapture(parsed)
+
 		if parsed.Op == syntax.OpConcat {
 			m.prefix, m.suffix, m.contains = optimizeConcatRegex(parsed)
 		}
diff --git a/model/labels/regexp_test.go b/model/labels/regexp_test.go
index 85cbe02a1f..d4385c7481 100644
--- a/model/labels/regexp_test.go
+++ b/model/labels/regexp_test.go
@@ -93,6 +93,7 @@ var (
 		"(.+)-(.+)-(.+)-(.+)-(.+)",
 		"((.*))(?i:f)((.*))o((.*))o((.*))",
 		"((.*))f((.*))(?i:o)((.*))o((.*))",
+		"(.*0.*)",
 	}
 	values = []string{
 		"foo", " foo bar", "bar", "buzz\nbar", "bar foo", "bfoo", "\n", "\nfoo", "foo\n", "hello foo world", "hello foo\n world", "",