diff --git a/storage/remote/otlptranslator/prometheusremotewrite/helper.go b/storage/remote/otlptranslator/prometheusremotewrite/helper.go
index 730486772e..1d321218e7 100644
--- a/storage/remote/otlptranslator/prometheusremotewrite/helper.go
+++ b/storage/remote/otlptranslator/prometheusremotewrite/helper.go
@@ -228,6 +228,9 @@ func (c *PrometheusConverter) addHistogramDataPoints(
 		}
 
 		pt := dataPoints.At(x)
+		// Clear stale exemplars from the previous data point to prevent
+		// them from leaking into _sum and _count of this data point.
+		appOpts.Exemplars = nil
 		timestamp := convertTimeStamp(pt.Timestamp())
 		startTimestamp := convertTimeStamp(pt.StartTimestamp())
 		baseLabels, err := c.createAttributes(pt.Attributes(), settings, reservedLabelNames, false, appOpts.Metadata)
diff --git a/storage/remote/otlptranslator/prometheusremotewrite/helper_test.go b/storage/remote/otlptranslator/prometheusremotewrite/helper_test.go
index c3fecc813b..f4f5283164 100644
--- a/storage/remote/otlptranslator/prometheusremotewrite/helper_test.go
+++ b/storage/remote/otlptranslator/prometheusremotewrite/helper_test.go
@@ -30,6 +30,7 @@ import (
 	"go.opentelemetry.io/collector/pdata/pmetric"
 
 	"github.com/prometheus/prometheus/config"
+	"github.com/prometheus/prometheus/model/exemplar"
 	"github.com/prometheus/prometheus/model/labels"
 	"github.com/prometheus/prometheus/model/metadata"
 	"github.com/prometheus/prometheus/prompb"
@@ -955,6 +956,121 @@ func TestPrometheusConverter_AddHistogramDataPoints(t *testing.T) {
 	}
 }
 
+// TestAddHistogramDataPoints_ExemplarLeakAcrossDataPoints verifies that
+// exemplars from a previous data point don't leak into _sum/_count of the
+// next data point. Regression test for stale exemplar leak.
+func TestAddHistogramDataPoints_ExemplarLeakAcrossDataPoints(t *testing.T) {
+	ts := pcommon.Timestamp(time.Now().UnixNano())
+	exTs := pcommon.Timestamp(time.Now().Add(time.Second).UnixNano())
+
+	metric := pmetric.NewMetric()
+	metric.SetName("test_hist")
+	metric.SetEmptyHistogram().SetAggregationTemporality(pmetric.AggregationTemporalityCumulative)
+
+	// First data point: has buckets and an exemplar with value 200 (> bound 100, so falls into +Inf).
+	pt1 := metric.Histogram().DataPoints().AppendEmpty()
+	pt1.SetTimestamp(ts)
+	pt1.SetStartTimestamp(ts)
+	pt1.SetSum(42)
+	pt1.SetCount(10)
+	pt1.ExplicitBounds().FromRaw([]float64{100})
+	pt1.BucketCounts().FromRaw([]uint64{7, 3})
+
+	ex := pt1.Exemplars().AppendEmpty()
+	ex.SetTimestamp(exTs)
+	ex.SetDoubleValue(200) // > 100, so falls into the +Inf bucket.
+
+	// Second data point: no exemplars.
+	pt2 := metric.Histogram().DataPoints().AppendEmpty()
+	pt2.SetTimestamp(ts)
+	pt2.SetStartTimestamp(ts)
+	pt2.SetSum(84)
+	pt2.SetCount(20)
+	pt2.ExplicitBounds().FromRaw([]float64{100})
+	pt2.BucketCounts().FromRaw([]uint64{14, 6})
+
+	appTest := teststorage.NewAppendable()
+	app := appTest.AppenderV2(t.Context())
+	converter := NewPrometheusConverter(app)
+	settings := Settings{}
+	resource := pcommon.NewResource()
+
+	require.NoError(t, converter.setResourceContext(resource, settings))
+	require.NoError(t, converter.setScopeContext(scope{}, settings))
+	require.NoError(t, converter.addHistogramDataPoints(
+		context.Background(),
+		metric.Histogram().DataPoints(),
+		settings,
+		storage.AOptions{
+			MetricFamilyName: metric.Name(),
+		},
+	))
+	require.NoError(t, app.Commit())
+
+	exConverted := exemplar.Exemplar{
+		Value: 200,
+		Ts:    convertTimeStamp(exTs),
+		HasTs: true,
+	}
+	tsMs := convertTimeStamp(ts)
+
+	want := []sample{
+		// -- First data point --
+		// _sum: no exemplars.
+		{
+			MF: "test_hist",
+			L:  labels.FromStrings(model.MetricNameLabel, "test_hist_sum"),
+			T:  tsMs, ST: tsMs, V: 42,
+		},
+		// _count: no exemplars.
+		{
+			MF: "test_hist",
+			L:  labels.FromStrings(model.MetricNameLabel, "test_hist_count"),
+			T:  tsMs, ST: tsMs, V: 10,
+		},
+		// le=100 bucket: no exemplars (exemplar value 200 > 100).
+		{
+			MF: "test_hist",
+			L:  labels.FromStrings(model.MetricNameLabel, "test_hist_bucket", model.BucketLabel, "100"),
+			T:  tsMs, ST: tsMs, V: 7,
+		},
+		// le=+Inf bucket: gets the exemplar.
+		{
+			MF: "test_hist",
+			L:  labels.FromStrings(model.MetricNameLabel, "test_hist_bucket", model.BucketLabel, "+Inf"),
+			T:  tsMs, ST: tsMs, V: 10,
+			ES: []exemplar.Exemplar{exConverted},
+		},
+		// -- Second data point --
+		// _sum: NO exemplars (this is the regression check).
+		{
+			MF: "test_hist",
+			L:  labels.FromStrings(model.MetricNameLabel, "test_hist_sum"),
+			T:  tsMs, ST: tsMs, V: 84,
+		},
+		// _count: NO exemplars (this is the regression check).
+		{
+			MF: "test_hist",
+			L:  labels.FromStrings(model.MetricNameLabel, "test_hist_count"),
+			T:  tsMs, ST: tsMs, V: 20,
+		},
+		// le=100 bucket: no exemplars.
+		{
+			MF: "test_hist",
+			L:  labels.FromStrings(model.MetricNameLabel, "test_hist_bucket", model.BucketLabel, "100"),
+			T:  tsMs, ST: tsMs, V: 14,
+		},
+		// le=+Inf bucket: no exemplars.
+		{
+			MF: "test_hist",
+			L:  labels.FromStrings(model.MetricNameLabel, "test_hist_bucket", model.BucketLabel, "+Inf"),
+			T:  tsMs, ST: tsMs, V: 20,
+		},
+	}
+
+	teststorage.RequireEqual(t, want, appTest.ResultSamples())
+}
+
 func TestGetPromExemplars(t *testing.T) {
 	ctx := context.Background()
 	c := NewPrometheusConverter(teststorage.NewAppendable().AppenderV2(t.Context()))