diff --git a/acme/setup.py b/acme/setup.py
index 91f83fade..8dace7abc 100644
--- a/acme/setup.py
+++ b/acme/setup.py
@@ -71,7 +71,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Intended Audience :: Developers',
diff --git a/certbot-apache/setup.py b/certbot-apache/setup.py
index bbf9fe67d..f1e2c8b5f 100644
--- a/certbot-apache/setup.py
+++ b/certbot-apache/setup.py
@@ -55,7 +55,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Environment :: Plugins',
diff --git a/certbot-ci/setup.py b/certbot-ci/setup.py
index f645b27a3..971db2b8e 100644
--- a/certbot-ci/setup.py
+++ b/certbot-ci/setup.py
@@ -40,7 +40,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 3 - Alpha',
         'Intended Audience :: Developers',
diff --git a/certbot-compatibility-test/setup.py b/certbot-compatibility-test/setup.py
index ed8073524..03298c122 100644
--- a/certbot-compatibility-test/setup.py
+++ b/certbot-compatibility-test/setup.py
@@ -38,7 +38,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 3 - Alpha',
         'Intended Audience :: Developers',
diff --git a/certbot-dns-cloudflare/setup.py b/certbot-dns-cloudflare/setup.py
index 54378c223..1f8fb2ea8 100644
--- a/certbot-dns-cloudflare/setup.py
+++ b/certbot-dns-cloudflare/setup.py
@@ -64,7 +64,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Environment :: Plugins',
diff --git a/certbot-dns-cloudxns/setup.py b/certbot-dns-cloudxns/setup.py
index 9ad73780b..7c7c4eda8 100644
--- a/certbot-dns-cloudxns/setup.py
+++ b/certbot-dns-cloudxns/setup.py
@@ -64,7 +64,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Environment :: Plugins',
diff --git a/certbot-dns-digitalocean/setup.py b/certbot-dns-digitalocean/setup.py
index b20d2c1e1..81dbcb943 100644
--- a/certbot-dns-digitalocean/setup.py
+++ b/certbot-dns-digitalocean/setup.py
@@ -65,7 +65,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Environment :: Plugins',
diff --git a/certbot-dns-dnsimple/setup.py b/certbot-dns-dnsimple/setup.py
index 39d579a4f..669a984a4 100644
--- a/certbot-dns-dnsimple/setup.py
+++ b/certbot-dns-dnsimple/setup.py
@@ -75,7 +75,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Environment :: Plugins',
diff --git a/certbot-dns-dnsmadeeasy/setup.py b/certbot-dns-dnsmadeeasy/setup.py
index 1e997a8e2..3fcb57483 100644
--- a/certbot-dns-dnsmadeeasy/setup.py
+++ b/certbot-dns-dnsmadeeasy/setup.py
@@ -64,7 +64,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Environment :: Plugins',
diff --git a/certbot-dns-gehirn/setup.py b/certbot-dns-gehirn/setup.py
index f26224926..21792edb9 100644
--- a/certbot-dns-gehirn/setup.py
+++ b/certbot-dns-gehirn/setup.py
@@ -63,7 +63,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Environment :: Plugins',
diff --git a/certbot-dns-google/setup.py b/certbot-dns-google/setup.py
index 940036340..df7597572 100644
--- a/certbot-dns-google/setup.py
+++ b/certbot-dns-google/setup.py
@@ -67,7 +67,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Environment :: Plugins',
diff --git a/certbot-dns-linode/setup.py b/certbot-dns-linode/setup.py
index c31ef05c9..646ca9acf 100644
--- a/certbot-dns-linode/setup.py
+++ b/certbot-dns-linode/setup.py
@@ -63,7 +63,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Environment :: Plugins',
diff --git a/certbot-dns-luadns/setup.py b/certbot-dns-luadns/setup.py
index f701a762e..c954a3a38 100644
--- a/certbot-dns-luadns/setup.py
+++ b/certbot-dns-luadns/setup.py
@@ -64,7 +64,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Environment :: Plugins',
diff --git a/certbot-dns-nsone/setup.py b/certbot-dns-nsone/setup.py
index 7bc49d4c4..8166558a9 100644
--- a/certbot-dns-nsone/setup.py
+++ b/certbot-dns-nsone/setup.py
@@ -64,7 +64,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Environment :: Plugins',
diff --git a/certbot-dns-ovh/setup.py b/certbot-dns-ovh/setup.py
index d3a0aedcf..e88c9eaca 100644
--- a/certbot-dns-ovh/setup.py
+++ b/certbot-dns-ovh/setup.py
@@ -64,7 +64,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Environment :: Plugins',
diff --git a/certbot-dns-rfc2136/setup.py b/certbot-dns-rfc2136/setup.py
index dfe063322..7f10fd1a1 100644
--- a/certbot-dns-rfc2136/setup.py
+++ b/certbot-dns-rfc2136/setup.py
@@ -64,7 +64,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Environment :: Plugins',
diff --git a/certbot-dns-route53/setup.py b/certbot-dns-route53/setup.py
index 8bbda7d7b..8d7826649 100644
--- a/certbot-dns-route53/setup.py
+++ b/certbot-dns-route53/setup.py
@@ -59,7 +59,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Environment :: Plugins',
diff --git a/certbot-dns-sakuracloud/setup.py b/certbot-dns-sakuracloud/setup.py
index 5ae092817..9197d3693 100644
--- a/certbot-dns-sakuracloud/setup.py
+++ b/certbot-dns-sakuracloud/setup.py
@@ -63,7 +63,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Environment :: Plugins',
diff --git a/certbot-nginx/setup.py b/certbot-nginx/setup.py
index f96839319..cebc3a1af 100644
--- a/certbot-nginx/setup.py
+++ b/certbot-nginx/setup.py
@@ -52,7 +52,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Environment :: Plugins',
diff --git a/certbot/setup.py b/certbot/setup.py
index 492dc12cd..87e045b74 100644
--- a/certbot/setup.py
+++ b/certbot/setup.py
@@ -133,7 +133,7 @@ setup(
     author="Certbot Project",
     author_email='client-dev@letsencrypt.org',
     license='Apache License 2.0',
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*, !=3.5.*',
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Environment :: Console',