diff --git a/certbot-dns-cloudxns/setup.py b/certbot-dns-cloudxns/setup.py
index df7dcc59a..3493638a0 100644
--- a/certbot-dns-cloudxns/setup.py
+++ b/certbot-dns-cloudxns/setup.py
@@ -11,7 +11,7 @@ version = '0.23.0.dev0'
 install_requires = [
     'acme>=0.21.1',
     'certbot>=0.21.1',
-    'dns-lexicon',
+    'dns-lexicon>=2.2.1', # Support for >1 TXT record per name
     'mock',
     'setuptools',
     'zope.interface',
diff --git a/certbot-dns-dnsimple/setup.py b/certbot-dns-dnsimple/setup.py
index a327edf93..f2887d371 100644
--- a/certbot-dns-dnsimple/setup.py
+++ b/certbot-dns-dnsimple/setup.py
@@ -11,7 +11,7 @@ version = '0.23.0.dev0'
 install_requires = [
     'acme>=0.21.1',
     'certbot>=0.21.1',
-    'dns-lexicon',
+    'dns-lexicon>=2.2.1', # Support for >1 TXT record per name
     'mock',
     'setuptools',
     'zope.interface',
diff --git a/certbot-dns-dnsmadeeasy/setup.py b/certbot-dns-dnsmadeeasy/setup.py
index 9ff317ee1..a3ee12cf0 100644
--- a/certbot-dns-dnsmadeeasy/setup.py
+++ b/certbot-dns-dnsmadeeasy/setup.py
@@ -11,7 +11,7 @@ version = '0.23.0.dev0'
 install_requires = [
     'acme>=0.21.1',
     'certbot>=0.21.1',
-    'dns-lexicon',
+    'dns-lexicon>=2.2.1', # Support for >1 TXT record per name
     'mock',
     'setuptools',
     'zope.interface',
diff --git a/certbot-dns-luadns/setup.py b/certbot-dns-luadns/setup.py
index 7b8ffd84f..f872d7093 100644
--- a/certbot-dns-luadns/setup.py
+++ b/certbot-dns-luadns/setup.py
@@ -11,7 +11,7 @@ version = '0.23.0.dev0'
 install_requires = [
     'acme>=0.21.1',
     'certbot>=0.21.1',
-    'dns-lexicon',
+    'dns-lexicon>=2.2.1', # Support for >1 TXT record per name
     'mock',
     'setuptools',
     'zope.interface',
diff --git a/certbot-dns-nsone/setup.py b/certbot-dns-nsone/setup.py
index 53b091065..102ed48c2 100644
--- a/certbot-dns-nsone/setup.py
+++ b/certbot-dns-nsone/setup.py
@@ -11,7 +11,7 @@ version = '0.23.0.dev0'
 install_requires = [
     'acme>=0.21.1',
     'certbot>=0.21.1',
-    'dns-lexicon',
+    'dns-lexicon>=2.2.1', # Support for >1 TXT record per name
     'mock',
     'setuptools',
     'zope.interface',
diff --git a/tools/dev_constraints.txt b/tools/dev_constraints.txt
index 47440241d..d02204215 100644
--- a/tools/dev_constraints.txt
+++ b/tools/dev_constraints.txt
@@ -12,7 +12,7 @@ botocore==1.7.41
 cloudflare==1.5.1
 coverage==4.4.2
 decorator==4.1.2
-dns-lexicon==2.1.14
+dns-lexicon==2.2.1
 dnspython==1.15.0
 docutils==0.14
 execnet==1.5.0