diff --git a/certbot-ci/src/certbot_integration_tests/certbot_tests/context.py b/certbot-ci/src/certbot_integration_tests/certbot_tests/context.py
index 4547ac713..1e323d4da 100644
--- a/certbot-ci/src/certbot_integration_tests/certbot_tests/context.py
+++ b/certbot-ci/src/certbot_integration_tests/certbot_tests/context.py
@@ -38,30 +38,34 @@ class IntegrationTestsContext:
         os.close(probe[0])
         self.hook_probe = probe[1]
 
-        self.manual_dns_auth_hook = (
-            '{0} -c "import os; import requests; import json; '
-            "assert not os.environ.get('CERTBOT_DOMAIN').startswith('fail'); "
-            "data = {{'host':'_acme-challenge.{{0}}.'.format(os.environ.get('CERTBOT_DOMAIN')),"
-            "'value':os.environ.get('CERTBOT_VALIDATION')}}; "
-            "request = requests.post('{1}/set-txt', data=json.dumps(data)); "
-            "request.raise_for_status(); "
-            '"'
-        ).format(sys.executable, self.challtestsrv_url)
-        self.manual_dns_auth_hook_allow_fail = (
-            '{0} -c "import os; import requests; import json; '
-            "data = {{'host':'_acme-challenge.{{0}}.'.format(os.environ.get('CERTBOT_DOMAIN')),"
-            "'value':os.environ.get('CERTBOT_VALIDATION')}}; "
-            "request = requests.post('{1}/set-txt', data=json.dumps(data)); "
-            "request.raise_for_status(); "
-            '"'
-        ).format(sys.executable, self.challtestsrv_url)
-        self.manual_dns_cleanup_hook = (
-            '{0} -c "import os; import requests; import json; '
-            "data = {{'host':'_acme-challenge.{{0}}.'.format(os.environ.get('CERTBOT_DOMAIN'))}}; "
-            "request = requests.post('{1}/clear-txt', data=json.dumps(data)); "
-            "request.raise_for_status(); "
-            '"'
-        ).format(sys.executable, self.challtestsrv_url)
+        self.manual_dns_auth_hook = self.generate_dns_auth_hook('_acme-challenge', True)
+        self.manual_dns_auth_hook_allow_fail = self.generate_dns_auth_hook('_acme-challenge', False)
+        self.manual_dns_persist_auth_hook = self.generate_dns_auth_hook('_validation-persist', True)
+        self.manual_dns_cleanup_hook = self.generate_dns_cleanup_hook('_acme-challenge')
+        self.manual_dns_persist_cleanup_hook = self.generate_dns_cleanup_hook('_validation-persist')
+
+    def generate_dns_auth_hook(self, challenge_subdomain: str, fail_on_subdomain: bool) -> str:
+        """Generates a python one-liner script which sets a DNS challenge TXT record challtestsrv URL,
+        and optionally fails if the subdomain starts with the word "fail" to simulate a faulty script"""
+        script_lines = ['import os', 'import requests', 'import json']
+        if fail_on_subdomain:
+            script_lines.append("assert not os.environ.get('CERTBOT_DOMAIN').startswith('fail')")
+        script_lines.append(f"data = {{'host':'{challenge_subdomain}.{{0}}.'.format("
+                            "os.environ.get('CERTBOT_DOMAIN')), 'value':"
+                            "os.environ.get('CERTBOT_VALIDATION')}")
+        script_lines.append(f"request = requests.post('{self.challtestsrv_url}/set-txt', data=json.dumps(data))")
+        script_lines.append("request.raise_for_status()")
+        script = '; '.join(script_lines)
+        return f'{sys.executable} -c "{script}"'
+
+    def generate_dns_cleanup_hook(self, challenge_subdomain: str) -> str:
+        """Generates a python one-liner script which cleans up the TXT record made by `generate_dns_auth_hook`"""
+        script_lines = ['import os', 'import requests', 'import json']
+        script_lines.append(f"data = {{'host':'{challenge_subdomain}.{{0}}.'.format(os.environ.get('CERTBOT_DOMAIN'))}}")
+        script_lines.append(f"request = requests.post('{self.challtestsrv_url}/clear-txt', data=json.dumps(data))")
+        script_lines.append("request.raise_for_status()")
+        script = '; '.join(script_lines)
+        return f'{sys.executable} -c "{script}"'
 
     def cleanup(self) -> None:
         """Cleanup the integration test context."""
diff --git a/certbot-ci/src/certbot_integration_tests/certbot_tests/test_main.py b/certbot-ci/src/certbot_integration_tests/certbot_tests/test_main.py
index afd902f5c..916d575cd 100644
--- a/certbot-ci/src/certbot_integration_tests/certbot_tests/test_main.py
+++ b/certbot-ci/src/certbot_integration_tests/certbot_tests/test_main.py
@@ -206,6 +206,22 @@ def test_manual_dns_auth(context: IntegrationTestsContext) -> None:
     assert_cert_count_for_lineage(context.config_dir, certname, 2)
 
 
+def test_manual_dns_persist_auth(context: IntegrationTestsContext) -> None:
+    """Test the DNS-PERSIST-01 challenge using manual plugin."""
+    certname = context.get_domain('dns-persist')
+    context.certbot([
+        '-a', 'manual', '-d', certname, '--preferred-challenges', 'dns-persist',
+        'run', '--cert-name', certname,
+        '--manual-auth-hook', context.manual_dns_persist_auth_hook,
+        '--manual-cleanup-hook', context.manual_dns_persist_cleanup_hook,
+        '--deploy-hook', misc.echo('deploy', context.hook_probe),
+    ])
+
+    assert_hook_execution(context.hook_probe, 'deploy')
+    assert_saved_deploy_hook(context.config_dir, certname)
+    assert_cert_count_for_lineage(context.config_dir, certname, 1)
+
+
 def test_certonly(context: IntegrationTestsContext) -> None:
     """Test the certonly verb on certbot."""
     context.certbot(['certonly', '--cert-name', 'newname', '-d', context.get_domain('newname')])
diff --git a/certbot-ci/src/certbot_integration_tests/utils/pebble_artifacts.py b/certbot-ci/src/certbot_integration_tests/utils/pebble_artifacts.py
index de9956847..7d7562b37 100644
--- a/certbot-ci/src/certbot_integration_tests/utils/pebble_artifacts.py
+++ b/certbot-ci/src/certbot_integration_tests/utils/pebble_artifacts.py
@@ -15,7 +15,7 @@ import requests
 from certbot_integration_tests.utils.constants import DEFAULT_HTTP_01_PORT
 from certbot_integration_tests.utils.constants import MOCK_OCSP_SERVER_PORT
 
-PEBBLE_VERSION = 'v2.8.0'
+PEBBLE_VERSION = 'v2.10.1'
 
 
 def fetch(workspace: str, http_01_port: int = DEFAULT_HTTP_01_PORT) -> tuple[str, str, str]: